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Dexamethasone + Gentamicin Eye Drops
Dosage
Packaging
What is Dexamethasone + Gentamicin?
Active Ingredients: Dexamethasone, Gentamicin Sulfate
Dexamethasone + Gentamicin Eye Drops are a combination drug for bacterial eye infections in dogs, poultry, and livestock animals like cows or sheep. This topical treatment helps reduce symptoms while also treating the underlying infection. It is indicated for conjunctivitis, keratitis, and blepharitis.
Dexamethasone belongs to a class of drugs known as corticosteroids. It works to decrease the immune system's response, which reduces symptoms like itching, swelling, redness, and allergic reactions. Dexamethasone works by inhibiting the release of inflammatory mediators, reducing capillary permeability, and suppressing immune response.
Before applying corticosteroids, it should be checked with fluorescein for ulcers. Before applying corticosteroids, it should be checked with fluorescein for ulcers, as this drug is contraindicated in cases of corneal ulcers. Many diseases require long-term topical use because the condition can only be controlled. Steroids are absorbed through the cornea and conjunctiva, and over a period of 2-3 weeks, they cause pituitary-adrenal suppression. Systemic absorption is minimal but it might occur after prolonged use. This type of medication should be applied with monitoring to ensure proper inflammation management. This corticosteroid is predominantly distributed in ocular tissues such as the cornea, aqueous humor, and anterior segment.
Gentamicin Sulfate is classified as an aminoglycoside antibiotic. It works by inhibiting protein synthesis within the bacteria. This antibiotic exerts bactericidal activity by binding to the bacterial 30S ribosomal subunit. This drug is poorly absorbed when applied topically but is absorbed well when the cornea is damaged or inflamed. Systemic absorption is typically low. This drug is distributed in the eye tissues and provides localized antibacterial effects by binding to these tissues.
This drug combination leads to anti-inflammatory and antibacterial actions.
Dexamethasone + Gentamicin Sulfate Eye Drops is produced and distributed by AdvaCare Pharma. This veterinary medicine has been manufactured in one of our strategically-located factories in China, India, and the USA. Our facilities undergo regular inspections to ensure they meet the standards necessary for GMP/ISO certification.
Why are we a trusted Dexamethasone + Gentamicin Eye Drops manufacturer?
AdvaCare Pharma is a global manufacturer of Dexamethasone + Gentamicin Sulfate Eye Drops for veterinary use. Our wide range of veterinary products can be adapted to meet your specific market needs, and we offer unrivaled support through the entire process - from supply chain coordination to document and registration support. We ensure our production facilities meet strict GMP guidelines so that our livestock medications are reliable and effective.
Uses
What are Dexamethasone + Gentamicin Eye Drops used for?
It's used to treat bacterial eye infections caused by susceptible microorganisms.
What animals can be treated with Dexamethasone + Gentamicin Sulfate Eye Drops?
This medicine is recommended for cattle, sheep, poultry, and dogs.
How are Dexamethasone + Gentamicin Eye Drops used?
This medication has been manufactured as a liquid intended for ophthalmic administration. Do not use it if the liquid has changed color or has become cloudy. Always check the expiration date on the package before applying these drops.
Why are Dexamethasone + Gentamicin Eye Drops used in companion animals?
In companion animals like dogs, these eye drops are used for treating eye infections and inflammatory conditions like conjunctivitis, keratitis, and anterior uveitis. This drug has a dual action and helps in controlling both infections and inflammations and leads to a faster recovery.
It is a product that is easy to administer to dogs and ensures that the medication is delivered directly to the site of the infection and inflammation. One study shows that Pseudomonas aeruginosa is susceptible to gentamicin and can be used as a topical treatment in dogs.
Why are Dexamethasone + Gentamicin Eye Drops used in cattle?
This medication in cattle can be used for treating Infectious Bovine Keratoconjunctivitis (pink eye). This is a contagious disease caused by Moraxella bovis that spreads during the summer months. It is mostly seen in younger animals. The most efficient treatment procedure is a combination of antibiotics and corticosteroids. It can relieve clinical signs such as conjunctivitis, corneal ulcerations, pain, pus matting, and tear staining of the face.
Are only these drops enough to treat pink eye in cattle?
In some mild cases, only these drops can help. In more severe cases, when there is an outbreak, all new animals need to be accommodated separately and away from the main herd. Fly control should be performed by using pour-on insecticides because it is transmitted by mechanical vectors. Studies suggest that an antibiotic sensitivity test needs to be performed to decide about the further treatment procedure.
Why are Dexamethasone + Gentamicin Eye Drops used in sheep?
This drug helps by reducing the inflammation and the pathogen that causes pink eye in sheep. It can also be used for various eye infections caused by susceptible bacteria.
Why are Dexamethasone + Gentamicin Eye Drops used in poultry?
These eye drops in poultry are used for treating bacterial conjunctivitis and respiratory infections that lead to secondary eye infections.
Can this medication be used for any eye-related condition?
It depends on the results of the antimicrobial tests. If the detected bacteria are susceptible to the antibiotic, this drug combination can be used in the treatment process. Veterinarians should perform a detailed examination before prescribing these drops.
Can Dexamethasone + Gentamicin be used if the animal is pregnant?
This is a topical drug and the distribution is very low. There is not enough scientific evidence if the drug reaches the placenta and leads to some side effects. Owners should inform their veterinarians if the animal is pregnant or lactating before applying this drug.
How should Dexamethasone + Gentamicin Eye Drops be stored?
This medication should be stored in a dark, dry location under 30°C. Keep the bottle tightly sealed when not in use. Discard the solution 28 days after opening.
What is the withdrawal period for Dexamethasone + Gentamicin Eye Drops?
A withdrawal period for the topical treatment of this medicine has not been established.
Dosage
How many Dexamethasone + Gentamicin Eye Drops should be given to large animals, such as cattle?
The usual dose is 4-5 drops per eye, given 4-5 times per day. Administer to the conjunctival sac. The duration of treatment should not exceed 10 days.
How much Dexamethasone + Gentamicin Eye Drops should be given to small animals, such as dogs?
The usual dose is 1-2 drops per eye, given 4-5 times per day. Administer to the conjunctival sac. The duration of treatment should not exceed 10 days.
Refer to a veterinary doctor or pharmacist for guidelines on dosage.
Side Effects
As with all pharmaceuticals, some unwanted effects can occur from the use of Dexamethasone + Gentamicin Eye Drops.
Some side effects may include but are not limited to: • mild irritation or stinging of the eyes
Serious side effects may include allergic reactions. If you notice this reaction, immediately contact a veterinarian professional.
For a comprehensive list of all possible side effects of this medication, consult a veterinarian.
Precautions
Do NOT use Dexamethasone + Gentamicin Eye Drops for an animal that:
- has a known allergy or hypersensitivity to any of the ingredients.
- has glaucoma or a corneal ulceration.
Treatment with this drug should be administered with caution in animals that are pregnant or lactating.
Owners should inform the veterinarians about the animal’s previous medical history and the drugs they are taking at the moment.
After administration, the animals should be carefully observed. If any unwanted effects occur, it should be reported to a veterinary professional.
Prolonged usage is not recommended unless the veterinarian suggests. It might lead to skin sensitization and the emergence of resistant organisms.
If you miss a dose, do not give two doses at once.
This drug should be kept in a cool and dry place.
What are the most common animals Dexamethasone + Gentamicin Eye Drops are used for?
Dexamethasone + Gentamicin Eye Drops are mainly used for treating eye infections caused by susceptible microorganisms. This includes treatment of the following microorganisms:
- Staphylococcus (Staphylococcus aureus and methicillin-sensitive strains of coagulase-negative Staphylococcus)
- Gram-negative bacteria
- Conjunctivitis
- Keratitis
- Dacryocystitis
- Eyelid inflammation
- Meibomian glands
- Various infections (Escherichia coli, Klebsiella, Proteus, Enterobacter, Serratia, and Pseudomonas aeruginosa)
Companion Animals Eye Infections
Dogs can be treated with these eye drops in cases of eye infections and inflammatory conditions like conjunctivitis, keratitis, and anterior uveitis.
Cattle Eye Infections
Cattle can be treated with these eye drops in cases of infectious bovine keratoconjunctivitis caused by Moraxella bovis. This combination of medications can reduce the bacterial load and the current inflammation.
Poultry Eye Infections
Dexamethasone + Gentamicin Sulfate Eye Drops in poultry can be used for treating bacterial conjunctivitis and respiratory infections that lead to secondary eye infections. The drops can also be used for treating eye-related symptoms.
Sheep Eye Infections
In sheep, these drops can be used for treating ovine infectious keratoconjunctivitis (pink eye). This condition is caused by Chlamydia psittaci or Mycoplasma conjunctivae. This medication can help in reducing inflammation and can manage infections. It can also be used for treating various eye conditions that are caused by susceptible bacteria.
Veterinarians should decide whether the drug is appropriate for the animal’s current health condition.
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