Tylosin Tartrate Soluble Powder

Active Ingredients: Tylosin Tartrate

Tylosin Tartrate Soluble Powder is an antibiotic drug used to treat various types of infections in poultry and livestock animals such as cows and pigs. It is indicated for the treatment of infections like bovine respiratory complex, metritis, and acute mastitis.

This drug is also indicated in the treatment of enteritis, pneumonia, erysipelas, infectious arthritis in swine, and soft tissue infections in small animals.

Tylosin Tartrate is classified as a macrolide antibiotic. It has been derived from the fermentation product of Streptomyces fradiae. Tylosin Tartrate shows a broad spectrum of activity against gram-positive organisms and a limited range of gram-negative organisms.

This antibiotic interferes with the protein synthesis by reversibly binding to the ribosomes. They prevent translocation and keep the peptide chain growing. It has the best effect on rapidly dividing bacteria and mycoplasmas. This antibiotic has a bacteriostatic property but also has bactericidal activity in high concentrations. It is effective in higher pH ranges (7.8-8) and can decrease the acidic environments in abscesses. It is a time-dependent antimicrobial agent, and its efficacy depends on the time exposure.

It also has an immunomodulatory effect and is used for treating respiratory infections. It is especially efficient in Pseudomonas aeruginosa infections. The effect depends on the concentrations against the susceptible bacteria.

This antibiotic is rapidly absorbed from the gastrointestinal tract, and then the macrolide is degraded by the gastric acid. After 1-2 hours, the plasma concentrations are at peak. The presence of food can delay the absorption process. The absorption in the ruminoreticulum is delayed and unreliable. Oral bioavailability for tylosin is 35%.

Then, the antibiotic is widely distributed in tissues, and the concentration is similar to that in plasma (or even higher). The drug accumulates in the cells, and the white blood cells contribute to the distribution by taking the drug to the inflammation site. The drug concentrates in the spleen, liver, kidneys, and lungs. The drug is not distributed to the eyes or the cerebrospinal fluid. This antibiotic can enter the pleural and ascitic fluid and address possible inflammation processes. More than 75% of the drug binds to the plasma proteins. Tylosin is eliminated in an active form. The excretion is mainly in bile (more than 60%) or via the enterohepatic way. Urinary clearance is slow and variable. The concentration of this antibiotic in milk is similar to that in plasma.

This drug is also available in the form of premix and injection.

It is important to note that Tylosin Tartrate Soluble Powder is for veterinary purposes only.

Tylosin Tartrate Soluble Powder is produced by AdvaCare Pharma. Our company offers a wide range of veterinary supplies that are available for global distribution.

Tylosin Soluble Powder is manufactured and globally supplied by AdvaCare Pharma. Our comprehensive range of 250+ GMP-certified veterinary medicines are adapted to meet the specific market needs and demands of our veterinary distributors. Equipped with an expert regulatory affairs team and advanced production capabilities, we are a Tylosin manufacturer with production capacity to manufacture more than 70 oral powder formulations that are cost-effective, efficacious and market-adapted for vet distributors, veterinarians and farmers worldwide.

What is Tylosin Tartrate used for?

What animals can be treated with Tylosin Tartrate Soluble Powder?

It's recommended for cows, sheep, and poultry.

How is Tylosin Tartrate Soluble Powder used?

This medicine has been manufactured as a water-soluble powder. It should be diluted with clean water and given to animals orally. It should be given as soon as possible.

How can Tylosin Tartrate Soluble Powder help in managing gastrointestinal infections?

This antibiotic is effective in treating gastrointestinal infections in poultry, cows, and pigs. Tylosin can help in alleviating gastrointestinal symptoms like diarrhea, vomiting, and stomach upset. When given on time, this antibiotic can prevent appetite loss and dehydration in animals. It is advisable to give this antibiotic with probiotics, vitamins, and minerals.

Tylosin is especially helpful in the treatment of enterococci and staphylococci in pigs. Staphylococcus hyicus can cause gastrointestinal changes in pigs. Treating the pigs with tylosin can help in the recovery process.

How can Tylosin Tartrate Soluble Powder help in treating respiratory infections?

This antibiotic can target certain bacteria and contribute to the healing process. Chronic respiratory disease in chickens is very common, and it leads to huge economic losses in the poultry industry. Proper dosages of tylosin can lead to normal weight gain and reduce the incidence of lesions. Tylosin can relieve the symptoms of pleuropneumonia in young chickens after treatment of 7 days.

The cause of this disease is M. gallisepticum which is sensitive to many broad-spectrum antibiotics. Tylosin can reduce egg transmission and is a prophylactic drug for preventing respiratory diseases in broilers and turkeys. It can also reduce the signs of difficulty breathing, coughing, or sneezing.

Is only Tylosin Tartrate Soluble Powder enough for treating certain diseases?

It depends on the stage of the disease. In some cases, this antibiotic is enough for a full recovery. But sometimes, a combination of drugs is needed. The drug of choice should be based on the antibiogram results.

Is Tylosin Tartrate Soluble Powder safe for pregnant or lactating animals?

No adverse effects are seen in pregnant or lactating animals after treatment with tylosin.

How should Tylosin Tartrate Soluble Powder be stored?

This medication should be stored in a dark, dry location under 30°C.

What is the withdrawal period for Tylosin Tartrate Soluble Powder?

The withdrawal period is 21 days for cattle and 14 days for swine. This medicine is not recommended for use in lactating dairy cattle. Do not use in calves to be slaughtered for veal.

This antibiotic is very lipophilic and tends to stay in milk for a very long time in low concentrations. Withdrawal time depends on the geolocation. Each country has different withdrawal periods for different antibiotics.

How much Tylosin Tartrate Soluble Powder should be given to pigs?

The usual dose is 25mg per kilogram of body weight.

How much Tylosin Tartrate Soluble Powder should be given to poultry?

The usual dose is 0.5g per liter of drinking water. The duration of treatment should last for 3-5 consecutive days.

The dose depends on the animal’s current health condition. It also depends on the animal species, weight, and veterinarian’s choice.

Refer to a veterinary doctor or pharmacist for guidelines on dosage.

As with all pharmaceuticals, some unwanted effects can occur from the use of Tylosin Tartrate Soluble Powder.

The side effects of macrolides depend on the animal species. Hypersensitivity reactions occur occasionally. This antibiotic might have hepatotoxic effects and can cause cholestasis.

In some cases, macrolides can lead to antimicrobial-induced colitis. Severe diarrhea in calves is also a common side effect after oral administration of macrolides.

Pigs can have edema of the rectal mucosa, mild anal protrusion, diarrhea, anal erythema, and pruritus.

Some animals can have cardiac toxicity (tachycardia and decreased contractility).

For a comprehensive list of all possible side effects of this medication, consult a veterinarian.

On the other side, cholesterol concentrations may decrease.

Tylosin should not be combined with chloramphenicol or lincosamide. This is because all of these antibiotics compete for the same 50S ribosomal subunit binding site. The activity of this antibiotic is depressed in acidic environments.

Prepare the drug with appropriate hygiene measures to avoid additional infections in animals.

If farmers or veterinarians miss a dose, do not apply extra doses. Overdosing can lead to adverse effects in animals. This includes gastrointestinal side effects like vomiting, diarrhea, or stomach upset.

Keep this drug out of reach of children and animals.

Poultry Bacterial Infections

Tylosin is efficient in the treatment process of many gastrointestinal infections in poultry. It can also be efficient in treating respiratory diseases like chronic respiratory disease in chickens.

Cow Bacterial Infections

This antibiotic is efficient in the treatment process of many gastrointestinal infections in cattle. It can also be efficient in treating respiratory diseases like the bovine respiratory complex or respiratory diseases caused by Pasteurella multocida.

Pig Bacterial Infections

In pigs, this antibiotic can help in managing enzootic pneumonia caused by M. hyopneumoniae. It is also helpful in managing and treating respiratory infections. Very often, it is used for treating erysipelas and infectious arthritis in swine.