- Home›
- Pharmaceuticals›
- Oncology Products›
- Oncology Powder for Injection›
- Bendamustine HCl for Injection
Bendamustine HCl for Injection
Dosage
Packaging
What is Bendamustine HCl?
Active Ingredients: Bendamustine HCl
Bendamustine HCl for Injection is an antineoplastic drug used in chemotherapy treatment for certain cancers of the blood. It is indicated for the treatment of chronic lymphocytic leukemia. It is also used to treat indolent non-Hodgkin's lymphoma that has been unresponsive to other treatments.
Bendamustine Hydrochloride is classified as an alkylating agent. It works by alkylating (adding an alkyl group) and cross-linking DNA, which causes DNA fragmentation, inhibition of protein synthesis, and cell death.
AdvaCare is a GMP manufacturer of Bendamustine HCl for Injection. We distribute a wide range of high-quality and cost-effective oncology medications. These medications have been manufactured in our facilities in China, India, and the USA.
Why choose us as your Bendamustine manufacturer?
AdvaCare Pharma manufactures Bendamustine Injection, one of 40+ oncology treatments, according to rigorous GMP protocols at our state-of-the-art production facility. We are committed to producing quality-assured, cost-effective cancer treatments that meet the highest industry standards and are readily available to cancer patients worldwide. As an established Bendamustine manufacturer, we supply pharmaceutical distributors, hospitals and government institutions with reliable cancer drugs.
Uses
What is Bendamustine HCl used for?
It is used to treat certain types of cancers, such as:
- chronic lymphocytic leukemia
- indolent B-cell non-Hodgkin lymphoma
How should Bendamustine HCl Powder for Injection be used?
This medication is manufactured as a powder and stored in a vial. The powder is to be prepared into a solution, and after reconstitution, it should be administered by slow injection into a vein.
As Bendamustine Hydrochloride for Injection is a cytotoxic drug, caution should be used when preparing and administering the solution. Goggles, gloves, and protective gowns are recommended.
What dosage should be used?
For chronic lymphocytic leukemia (CLL), the usual dose is 100mg/m² per dose, given on days 1 and 2 of a 28 day cycle. The cycle can be repeated up to 6 times.
For indolent B-cell non-Hodgkin lymphoma, the usual dose is 120mg/m² per dose, given on days 1 and 2 of a 28 day cycle. The cycle can be repeated up to 8 times.
However, the exact dosage is dependent on the patient and treatment plan, refer to a doctor or pharmacist for guidelines on dosage. Do not exceed what they advise.
Side Effects
As with all pharmaceuticals, some unwanted effects can occur from the use of Bendamustine HCl for Injection.
Common side effects include, but may not be limited to:
- gastrointestinal effects (vomiting, diarrhea, upset stomach)
- fever or cough
- rash
- headache
Seek medical attention if the following develop:
- fever or chills during or after treatment
- signs of infection at the injection site
- severe gastrointestinal effects that do not subside
- signs of a liver problem
- signs of low blood cell count
- signs of tumor cell breakdown
For a comprehensive list of all possible effects, consult a doctor.
If any symptoms persist or worsen, or you notice any other symptoms, please call your doctor immediately.
Precautions
Do NOT use Bendamustine HCl for Injection if: • You are allergic to any component of the powder.
Consult with a doctor about any medications you are taking before treatment with Bendamustine HCl for Injection. This drug is known to interact with allopurinol, as well as other medications.
Do not take Bendamustine Hydrochloride during pregnancy, as it may cause birth defects. It is important for both women and men being treated with this drug to use an effective method of birth control. For women, continue birth control for at least 6 months after treatment, and at least 3 months after treatment for men. Inform a doctor as soon as possible if pregnancy occurs during treatment with Bendamustine HCl. Do not breastfeed for at least 1 week after treatment.
Bendamustine HCl may not be suitable for patients with certain conditions, including:
- weakened immune function
- current infection
- tuberculosis
- herpes zoster
- electrolyte imbalance
- liver or kidney disease
- current smoker
Driving or operating machinery should be safe, as the medication not cause any relevant symptoms, but individual reactions to the medication may vary.
You might be interested in...
Why AdvaCare Pharma?
As an industry leader, we are aware of our responsibility to provide affordable and sustainable solutions to improve healthcare worldwide.