Dexamethasone Injection

Active Ingredients: Dexamethasone

Dexamethasone Injection is a corticosteroid drug used to treat inflammatory conditions in many types of animals, including cows, camels, cats, dogs, goats, horses, and sheep. It is indicated for ketosis, and it's used to treat symptoms related to various rheumatic, allergic, and dermatologic diseases.

Dexamethasone belongs to a class of drugs known as corticosteroids. The active ingredient, dexamethasone, works to decrease the immune system's response, which reduces symptoms like itching, swelling, redness, and allergic reactions. Being a strong anti-inflammatory agent, it targets multiple pathways in the inflammatory response. Its pharmacological action is more enduring and potent than naturally occurring corticosteroids, giving it a favorable profile for specific clinical scenarios.

The conditions that this drug is typically used for include rheumatoid arthritis, allergic reactions, and various skin disorders like eczema or dermatitis. In livestock, it has proven effective against bovine ketosis, a metabolic disorder in cattle. In horses, it is often utilized to alleviate symptoms of laminitis, a painful inflammation of the hoof.

When considering Dexamethasone Injection for animals, its pharmacokinetics and biodistribution should be understood. This medication has a rapid onset of action and a longer half-life than some other corticosteroids, allowing for sustained therapeutic effects. Its versatile formulation also enables it to be used both systemically and locally, depending on the clinical need.

It is important to note that AdvaCare's Dexamethasone Injection is for veterinary purposes only, and whilst there are types available for human use, you should only use the kind that has been prescribed by a veterinary doctor or animal care specialist for an animal. Administering the incorrect formulation or dosage can result in adverse effects or diminished therapeutic outcomes in the treated animals.

This product in particular stands out due to its adherence to rigorous quality standards. Tailored for managing inflammation, its straightforward mechanism provides rapid relief to afflicted animals. Veterinarians can rely on its consistent performance across a range of use cases, while its versatile formulation allows for adaptability in different scenarios.

AdvaCare Pharma is a GMP-certified manufacturer of Dexamethasone Injections. We offer a broad range of high-quality veterinary medications available for distribution. Partnering with AdvaCare ensures veterinarians and animal care providers access to reliable solutions for diverse animal health needs.

Dexamethasone Injection is manufactured and globally distributed by AdvaCare Pharma, a leading manufacturer of veterinary injections in the pharmaceutical industry. We have been committed to distributing high-quality, GMP-certified veterinary medications for the global market over the past 20 years. As a top Dexamethasone manufacturer, we ensure that all of our 100+ veterinary injections surpass our distributors' requirements by conducting routine internal and third-party facility audits.

What is Dexamethasone used for?

What animals can be treated with Dexamethasone Injection?

This medicine is recommended for horses, companion animals, and livestock animals like cows, goats, and sheep.

How does the drug work?

Dexamethasone acts by mimicking the effects of natural corticosteroid hormones produced by the adrenal glands. It targets specific cells and receptors in the body, inhibiting the release of inflammation-causing substances. By suppressing both the inflammatory and immune responses, Dexamethasone manages and alleviates various inflammatory conditions.

How is a Dexamethasone Injection used?

This medication has been manufactured as a liquid, which is packaged in a vial. It is intended to be administered by intramuscular or intravenous injection. Using a sterile syringe and needle is crucial. Dexamethasone Injection is intended for veterinary use only.

How quickly can effects be seen after administering the injection?

The onset of action is rapid, with effects generally seen within hours, but the duration of effect can vary depending on the dose and the condition.

How is the dosage of Dexamethasone Injection determined?

The dosage depends on the severity of the condition being treated, the specific animal species, and its weight.

What is the withdrawal period for Dexamethasone when given by injection?

For meat, 21 days. For milk, 5 days. This means that after the last dose of Dexamethasone has been administered, one must wait 21 days before the meat of that animal is considered safe for human consumption. Milk produced by the animal should not be consumed for 5 days post-treatment.

What are the potential side effects of prolonged Dexamethasone use in animals?

Chronic use might lead to side effects such as immune suppression, muscle weakness, gastrointestinal disturbances, and changes in behavior or mood.

Is Dexamethasone safe for use in all age groups of animals?

The safety profile may vary with age. Younger animals might be more prone to certain side effects. Always consult a veterinarian before administering.

Is there any resistance reported with prolonged use?

Unlike antibiotics, resistance is not a typical concern with corticosteroids like Dexamethasone. However, prolonged or inappropriate use can lead to decreased efficacy, mainly due to changes in corticosteroid receptor responsiveness in the animal.

How does Dexamethasone compare to other corticosteroids in terms of potency?

Dexamethasone is more potent than many other corticosteroids, often requiring lower dosages to achieve similar therapeutic effects. It also has a longer half-life compared to medications like prednisone or hydrocortisone.

How should Dexamethasone Injection be stored?

This medication should be stored in a dark, dry location between 2-15°C. The vial should be sealed tightly when not in use. If the entire vial isn't used in one go, the remaining solution should be stored in a cool, dry place, away from light. Note the date of opening and ensure the solution is used within the recommended time frame.

How much Dexamethasone Injection should be given to cows?

The usual dose is 5-20mg, given IV/IM.

How much Dexamethasone Injection should be given to dogs or cats?

The usual dose is 0.25-1.0mg, given IV/IM.

How much Dexamethasone Injection should be given to horses?

The usual dose is 2-5mg, given IV/IM.

How much Dexamethasone Injection should be given to goats or sheep?

The usual dose is 0.1-0.3mg/kg, given IV/IM.

How much Dexamethasone Injection should be given to poultry?

For chickens and turkeys, the typical dose is 0.1-0.5mg/kg, given IV/IM.

What should be done if a dose is missed?

A missed dose should be administered as soon as possible. However, if it's close to the time for the next one, skip the missed dose and return to the regular schedule. Do not double up on doses to make up for the missed one, and always consult with a veterinarian prior to administration.

What should be done if an overdose of Dexamethasone Injection is suspected?

Seek veterinary attention immediately. Overdosing can lead to heightened side effects, including severe immunosuppression, gastrointestinal disturbances, and metabolic abnormalities. Symptoms of overdose include increased thirst and urination, excessive panting in dogs or increased respiratory rate in other animals, abdominal distention or bloating, prolonged appetite loss or sudden weight gain, and muscle weakness or atrophy.

Refer to a veterinary doctor or pharmacist for guidelines on dosage.

As with all pharmaceuticals, some unwanted effects can occur from the use of Dexamethasone Injection.

Serious side effects may include allergic reactions.

Immediate veterinary attention is essential if an overdose is suspected.

For a comprehensive list of all possible side effects of this medication, consult a veterinarian.

Do not administer a vaccine while the animal is undergoing treatment with a corticosteroid. Vaccination at this time may compromise the immune response, rendering the vaccine less effective or possibly increasing the risk of adverse reactions.

This drug should not be injected rapidly. Administering the medication too quickly can lead to hypotension (a sudden drop in blood pressure), which might require emergency intervention. Rapid injection may cause hemolytic anemia, a condition where the red blood cells are destroyed faster than they can be produced, compromising the animal's ability to carry oxygen effectively. Ensure that the injection is delivered at a measured pace.